Kashkadarya region is one of the regions of Uzbekistan, located in the south-eastern part of the country in the basin of the Kashkadarya River and on the western slopes of the Pamir-Alay mountains. It borders with Tajikistan, Turkmenistan, Samarkand Region, Bukhara Region, and Surxandarya Region. Karshi is the capital of Kashkadarya Region. Karshi is a city in southern Uzbekistan.